BDBM50130753 CHEMBL3634396

SMILES [H][C@@]12CCC[C@H](N3CCCC3)[C@]1([H])N(CCN2C(=O)OC)C(=O)Cc1ccc(Cl)c(Cl)c1

InChI Key InChIKey=PAVYSOUZQLFNIW-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130753   

TargetKappa-type opioid receptor(Human)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130753(CHEMBL3634396)
Affinity DataEC50:  351nMAssay Description:Agonist activity at kappa opioid receptor in human HEK293 cells after 30 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130753(CHEMBL3634396)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]-U-69593 from kappa opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Mercachem

Curated by ChEMBL
LigandPNGBDBM50130753(CHEMBL3634396)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to kappa opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMed