BDBM50130655 2-Chloro-4-[5-(4-fluoro-phenyl)-2-methylsulfanyl-3H-imidazol-4-yl]-pyridine::2-chloro-4-(4-(4-fluorophenyl)-2-(methylthio)-1H-imidazol-5-yl)pyridine::CHEMBL113060

SMILES CSc1nc(c([nH]1)-c1ccc(F)cc1)-c1ccnc(Cl)c1

InChI Key InChIKey=IVMWZPRCCDVEDY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130655   

TargetMitogen-activated protein kinase 14(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50130655(2-chloro-4-(4-(4-fluorophenyl)-2-(methylthio)-1H-i...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50130655(2-chloro-4-(4-(4-fluorophenyl)-2-(methylthio)-1H-i...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against TNF-alpha release in PBM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11/12/13/14(Human)
Eberhard-Karls-University T£Bingen

Curated by ChEMBL
LigandPNGBDBM50130655(2-chloro-4-(4-(4-fluorophenyl)-2-(methylthio)-1H-i...)
Affinity DataIC50: 350nMAssay Description:Inhibitory activity against induction of IL-1-beta release in PBMCsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed