BDBM50130551 2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl)-3-{3-[4-(methanesulfonylamino-methyl)-benzyl]-thioureido}-propyl ester::CHEMBL107115

SMILES Cc1ccc(CC(CNC(=S)NCc2ccc(CNS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C

InChI Key InChIKey=KCKPPZGMDMBRQY-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130551   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130551(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataEC50:  1.70E+3nMAssay Description:In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130551(2,2-Dimethyl-propionic acid 2-(3,4-dimethyl-benzyl...)
Affinity DataKi:  3.00E+3nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]RTX displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed