BDBM50130544 Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-methanesulfonylamino-3-methoxy-benzyl)-thioureido]-propyl ester::CHEMBL107861

SMILES COc1cc(CNC(=S)NCC(COC(=O)c2ccccc2)Cc2ccc(cc2)C(C)(C)C)ccc1NS(C)(=O)=O

InChI Key InChIKey=JBZKRRIUKPZZGP-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130544   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130544(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)
Affinity DataEC50:  252nMAssay Description:In vitro [Ca2+] influx relative to capsaicin by Rat Vanilloid receptor (VR1) expressing CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50130544(Benzoic acid 2-(4-tert-butyl-benzyl)-3-[3-(4-metha...)
Affinity DataKi:  77.2nMAssay Description:In vitro binding affinity towards Rat Vanilloid receptor 1 (VR1) by [3H]RTX displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed