BDBM50130505 CHEMBL3634101

SMILES Clc1cccc(COc2cc3cncnc3cc2NC(=O)Nc2cccc3ccccc23)c1

InChI Key InChIKey=CIGZUVLALLRNKR-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50130505   

TargetTranslocator protein(Rat)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 722nMAssay Description:Displacement of [3H]PK11195 from TSPO receptor in Sprague-Dawley rat cerebral cortex membrane by radiometric competitive assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]astemizole from human ERG potassium channel expressed in HEK293 cell membrane after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Korea University of Science and Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50130505(CHEMBL3634101)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2016
Entry Details Article
PubMed