BDBM50130440 CHEMBL104720::Cyclopropanecarboxylic acid [3-(1-methyl-piperidin-4-yl)-1H-pyrrolo[3,2-b]pyridin-5-yl]-amide

SMILES CN1CCC(CC1)c1c[nH]c2ccc(NC(=O)C3CC3)nc12

InChI Key InChIKey=LVNGFTRMMWFHRF-UHFFFAOYSA-N

Data  4 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50130440   

Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130440(Cyclopropanecarboxylic acid [3-(1-methyl-piperidin...)
Affinity DataEC50:  34nMAssay Description:In vitro effective concentration for stimulation of [35S]GTP-gamma-S, binding in mouse LM(tk-)cells expressing the human 5-hydroxytryptamine 1F recep...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130440(Cyclopropanecarboxylic acid [3-(1-methyl-piperidin...)
Affinity DataKi:  9.80nMAssay Description:In vitro binding affinity was determined by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130440(Cyclopropanecarboxylic acid [3-(1-methyl-piperidin...)
Affinity DataKi:  1.40E+3nMAssay Description:In vitro binding affinity by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130440(Cyclopropanecarboxylic acid [3-(1-methyl-piperidin...)
Affinity DataKi:  1.70E+3nMAssay Description:In vitro binding affinity by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1D(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50130440(Cyclopropanecarboxylic acid [3-(1-methyl-piperidin...)
Affinity DataKi:  1.80E+3nMAssay Description:In vitro binding affinity by radioligand binding assay using cell line expressing human 5-hydroxytryptamine 1D receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed