BDBM50130371 2-[3-(3-Ethyl-2-oxo-azepan-3-yl)-phenoxy]-4-imidazol-1-ylmethyl-benzonitrile::CHEMBL321796

SMILES CCC1(CCCCNC1=O)c1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1

InChI Key InChIKey=YIHOJJQZGPJKGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130371   

LigandPNGBDBM50130371(2-[3-(3-Ethyl-2-oxo-azepan-3-yl)-phenoxy]-4-imidaz...)
Affinity DataIC50: 1.30nMAssay Description:Concentration required to inhibit recombinant human farnesyltransferase (FTase) catalyzed incorporation of [3H]FPP into recombinant Ras-CVIM.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50130371(2-[3-(3-Ethyl-2-oxo-azepan-3-yl)-phenoxy]-4-imidaz...)
Affinity DataIC50: 20nMAssay Description:Concentration required to inhibit recombinant human geranylgeranyl transferase type I (GGTase-I) catalyzed incorporation of [3H]GGPP to the C-terminu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed