BDBM50130287 (4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-3-yl)-amine::CHEMBL92221

SMILES [#6]-c1c(cccc1-c1ccccc1)\[#7]=[#6]-1/[#7]-[#6]-[#6]-[#7]-1

InChI Key InChIKey=KKJVPLDLUKVODK-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50130287   

Target5-hydroxytryptamine receptor 7(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  16nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 7 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  16nMAssay Description:Inhibition of [3H]-5-CT binding to 5-hydroxytryptamine 7 receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  16nMAssay Description:Binding affinity at rat 5-hydroxytryptamine 7 receptor.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetAlpha-2A adrenergic receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  19nMAssay Description:Binding affinity towards Alpha-2 adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  19nMAssay Description:Affinity for Alpha-2 adrenergic receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  200nMAssay Description:Binding affinity towards alpha-1-adrenergic receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50130287((4,5-Dihydro-1H-imidazol-2-yl)-(2-methyl-biphenyl-...)
Affinity DataKi:  209nMAssay Description:Affinity for Alpha-1 adrenergic receptor of rat cortical membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details Article
PubMed