BDBM50130063 (R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-phenyl-ethyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide::(R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-phenyl-ethyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide::CHEMBL78055

SMILES NC(=N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](Cc1ccccc1)NS(=O)(=O)Cc1ccccc1)C(=O)c1nccs1

InChI Key InChIKey=UTHIXVNTGHQWPR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50130063   

TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 42nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 27nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 27nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human alpha-thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130063((R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human factor 7aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed