BDBM50130061 (R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-m-tolyl-ethyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide::(R)-N-{1-[(S)-(S)-4-Guanidino-1-(thiazole-2-carbonyl)-butylcarbamoyl]-2-m-tolyl-ethyl}-3-phenyl-2-phenylmethanesulfonylamino-propionamide::CHEMBL78057

SMILES Cc1cccc(C[C@H](NC(=O)[C@@H](Cc2ccccc2)NS(=O)(=O)Cc2ccccc2)C(=O)N[C@@H](CCCNC(N)=N)C(=O)c2nccs2)c1

InChI Key InChIKey=YNNVWEQXPMIAIP-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50130061   

TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 170nMAssay Description:Inhibition of tissue coagulation factor VIIMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 160nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against thrombin (IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 160nMAssay Description:Inhibitory activity against coagulation factor X.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against thrombin (IIa).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
Pharmacia

Curated by ChEMBL
LigandPNGBDBM50130061((R)-N-{(S)-1-[(S)-4-Guanidino-1-(thiazole-2-carbon...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against tissue coagulation factor VII.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed