BDBM50130015 8-(4-Methyl-piperazin-1-yl)-2-(2-methyl-pyridin-4-ylmethyl)-1-oxo-4-(3,4,5-trimethoxy-phenyl)-1,2-dihydro-[2,7]naphthyridine-3-carboxylic acid methyl ester::CHEMBL77893

SMILES COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccnc(N3CCN(C)CC3)c2c(=O)n1Cc1ccnc(C)c1

InChI Key InChIKey=WRKDNJAMFYODKH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50130015   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Dog)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50130015(8-(4-Methyl-piperazin-1-yl)-2-(2-methyl-pyridin-4-...)
Affinity DataIC50: 94nMAssay Description:Inhibitory activity against phosphodiesterase 5 (PDE5) isolated from canine lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetP04972/P11541/P16586/P22571/P23439/Q95142(Bovine)
Tanabe Seiyaku

Curated by ChEMBL
LigandPNGBDBM50130015(8-(4-Methyl-piperazin-1-yl)-2-(2-methyl-pyridin-4-...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibitory activity against Phosphodiesterase 6 isolated from bovine retinaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
LigandPNGBDBM50130015(8-(4-Methyl-piperazin-1-yl)-2-(2-methyl-pyridin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against phosphodiesterase-1 (PDE1) isolated from canine lungMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed