BDBM50129957 2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7-yl]-2-methyl-propionic acid ethyl ester::CHEMBL75255

SMILES CCOC(=O)C(C)(C)c1ccc2c(C)cc(Oc3ccc(cc3)C(N)=N)nc2c1

InChI Key InChIKey=NQTRMKQQZOHULE-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50129957   

TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against thrombin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibitory activity against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against plasmin in human plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlasminogen(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50129957(2-[2-(4-Carbamimidoyl-phenoxy)-4-methyl-quinolin-7...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed