BDBM50129784 4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylaniline::CHEMBL328430::[4-(6-Methoxy-benzothiazol-2-yl)-phenyl]-dimethyl-amine

SMILES COc1ccc2nc(sc2c1)-c1ccc(cc1)N(C)C

InChI Key InChIKey=POFIKJKJPDPHTI-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50129784   

TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50129784(4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50129784(4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...)
Affinity DataIC50: 700nMAssay Description:Inhibition of luciferin binding site of Photinus pyralis luciferase by competitive inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Pennsylania firefly)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50129784(4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of luciferin binding site of Photuris pennsylvanica luciferase by competitive KinaseGlo luminescent assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Csir-Indian Institute of Chemical Technology (CSIR-IICT)

Curated by ChEMBL
LigandPNGBDBM50129784(4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...)
Affinity DataKd:  220nMAssay Description:Binding affinity to amyloid beta (1 to 40) (unknown origin) aggregates assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetAmyloid-beta precursor protein(Human)
Csir-Indian Institute of Chemical Technology (CSIR-IICT)

Curated by ChEMBL
LigandPNGBDBM50129784(4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...)
Affinity DataKi:  1.90nMAssay Description:Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed