BDBM50129503 6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyran-2-one::CHEMBL71200

SMILES CCOc1cc(-c2ccccc2)c(-c2ccc(cc2)S(C)(=O)=O)c(=O)o1

InChI Key InChIKey=CXFWNCNJNGMYQT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50129503   

TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50129503(6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 2.82E+5nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50129503(6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Bovine)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50129503(6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 1.30E+3nMAssay Description:In vitro inhibitory activity against prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50129503(6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 2.82E+5nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 1 (COX-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50129503(6-Ethoxy-3-(4-methanesulfonyl-phenyl)-4-phenyl-pyr...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of ovine COX-2 using arachidonic acid as substrate preincubated for 2 mins followed by substrate addition and measured after 2 mins by EIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed