BDBM50129359 CHEMBL67558::[6-(4-Bromo-2,6-dimethyl-phenylcarbamoyl)-benzothiazol-2-yl]-carbamic acid tert-butyl ester

SMILES Cc1cc(Br)cc(C)c1NC(=O)c1ccc2nc(NC(=O)OC(C)(C)C)sc2c1

InChI Key InChIKey=LSMVVLORUAYUFU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129359   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50129359([6-(4-Bromo-2,6-dimethyl-phenylcarbamoyl)-benzothi...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed