BDBM50129358 2-[3-(1-Phenyl-propyl)-ureido]-benzothiazole-6-carboxylic acid (2-chloro-6-methyl-phenyl)-amide::CHEMBL304300

SMILES CCC(NC(=O)Nc1nc2ccc(cc2s1)C(=O)Nc1c(C)cccc1Cl)c1ccccc1

InChI Key InChIKey=NGFDDWYJIWZAEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129358   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50129358(2-[3-(1-Phenyl-propyl)-ureido]-benzothiazole-6-car...)
Affinity DataIC50: 19nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed