BDBM50129339 2-(3-tert-Butyl-ureido)-benzothiazole-6-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL302073

SMILES Cc1cc(C)c(NC(=O)c2ccc3nc(NC(=O)NC(C)(C)C)sc3c2)c(C)c1

InChI Key InChIKey=ARRPUFWMDUJPDE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129339   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50129339(2-(3-tert-Butyl-ureido)-benzothiazole-6-carboxylic...)
Affinity DataIC50: 70nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed