BDBM50129328 CHEMBL65785::[6-(2,4,6-Trimethyl-phenylcarbamoyl)-1H-benzoimidazol-2-yl]-carbamic acid tert-butyl ester

SMILES Cc1cc(C)c(NC(=O)c2ccc3nc(NC(=O)OC(C)(C)C)[nH]c3c2)c(C)c1

InChI Key InChIKey=DVMZOFCNOFJNSW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129328   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50129328([6-(2,4,6-Trimethyl-phenylcarbamoyl)-1H-benzoimida...)
Affinity DataIC50: 3.23E+3nMAssay Description:In vitro inhibition of phosphorylation of an exogenous substrate by human p56 Lck tyrosine kinase expressed as a His-tagged protein in insect cells u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed