BDBM50129162 8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::8-methoxy-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::CHEMBL303293

SMILES COc1ccc-2c(OCc3c-2ccc2NC(C)(C)C=C(C)c32)c1

InChI Key InChIKey=AFIHLGIDZOZFPH-UHFFFAOYSA-N

Data  2 KI  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50129162   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129162(8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataEC50:  193nMAssay Description:Effective concentration for antagonistic activity towards human progesterone in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129162(8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataEC50: >1.00E+3nMAssay Description:Effective concentration for human progesterone in T47D human breast cancer cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129162(8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataIC50: 514nMAssay Description:Inhibition of human progesterone in T47D human breast cancer cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129162(8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataKi:  355nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129162(8-Methoxy-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-a...)
Affinity DataKi:  357nMAssay Description:Binding towards human progesterone receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed