BDBM50129148 CHEMBL65689::[9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-chrysen-(5Z)-ylidene]-acetaldehyde

SMILES CC1=CC(C)(C)Nc2ccc3-c4cc(F)ccc4O\C(=C/C=O)c3c12

InChI Key InChIKey=DWRXZZOJNRAGLX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129148   

TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129148([9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-...)
Affinity DataIC50: 243nMAssay Description:Inhibitory concentration for antagonistic activity towards human progesterone receptor (hPR) using the cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetProgesterone receptor(Human)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129148([9-Fluoro-2,2,4-trimethyl-1,2-dihydro-6-oxa-1-aza-...)
Affinity DataKi: >100nMAssay Description:Binding affinity for human progesterone receptor; Not activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed