BDBM50128920 (3R,3aS)-7-[3-(3-Chloro-benzylamino)-propyl]-2,3,3a,9b-tetrahydro-1H-cyclopenta[c]quinolin-4-ylamine::CHEMBL162416::CHEMBL545441

SMILES NC1=Nc2cc(CCCNCc3cccc(Cl)c3)ccc2[C@H]2CCC[C@@H]12

InChI Key InChIKey=TXHAPORLDDIXMY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50128920   

TargetNitric oxide synthase, inducible(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50128920(CHEMBL545441 | CHEMBL162416 | (3R,3aS)-7-[3-(3-Chl...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50128920(CHEMBL545441 | CHEMBL162416 | (3R,3aS)-7-[3-(3-Chl...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50128920(CHEMBL545441 | CHEMBL162416 | (3R,3aS)-7-[3-(3-Chl...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50128920(CHEMBL545441 | CHEMBL162416 | (3R,3aS)-7-[3-(3-Chl...)
Affinity DataIC50: 42nMAssay Description:Inhibitory concentration against recombinant human (neuronal nitric oxide synthase) n-NOSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50128920(CHEMBL545441 | CHEMBL162416 | (3R,3aS)-7-[3-(3-Chl...)
Affinity DataIC50: 580nMAssay Description:Inhibitory concentration against human Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Schering

Curated by ChEMBL
LigandPNGBDBM50128920(CHEMBL545441 | CHEMBL162416 | (3R,3aS)-7-[3-(3-Chl...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibitory concentration against recombinant human Endothelial nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed