BDBM50128901 CHEMBL58502::Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hydroxy-2-octadecanoylamino-octadec-4-enyl ester

SMILES CCCCCCCCCCCCCCCCCC(=O)N[C@@H](COC(=O)NCc1ccncc1)[C@H](O)\C=C\CCCCCCCCCCCCC

InChI Key InChIKey=MZPPVXASDZXKGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128901   

TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128901(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory concentration against the membrane neutral magnesium-dependent Sphingomyelinase (N-SMase) using rat brain microsomes as the enzyme sourceMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetSphingomyelin phosphodiesterase 2(Rat)
Taisho Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50128901(Pyridin-4-ylmethyl-carbamic acid (E)-(2S,3R)-3-hyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of rat brain microsomes nSMaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed