BDBM50128879 CHEMBL59512::[3-(4-Chloro-phenyl)-3-pyridin-2-yl-propyl]-[4-(1H-imidazol-4-yl)-butyl]-amine

SMILES Clc1ccc(cc1)C(CCNCCCCc1cnc[nH]1)c1ccccn1

InChI Key InChIKey=YZQOOIBEGBPDFU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128879   

TargetHistamine H3 receptor(Guinea pig)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50128879([3-(4-Chloro-phenyl)-3-pyridin-2-yl-propyl]-[4-(1H...)
Affinity DataKi:  10nMAssay Description:Binding affinity against H3 receptor in guinea pig brain using [3H]N-alpha-methyl histamine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetHistamine H1 receptor(Rat)
The Schering Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50128879([3-(4-Chloro-phenyl)-3-pyridin-2-yl-propyl]-[4-(1H...)
Affinity DataKi:  254nMAssay Description:Ability to displace [3H]pyrilamine from histamine H1 receptor in male Sprague-Dawley rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed