BDBM50128795 4-(2-Bromo-phenyl)-6-(3,4-dihydroxy-phenyl)-5-nitro-1-pyridin-3-ylmethyl-piperidin-2-one::CHEMBL310450

SMILES Oc1ccc(cc1O)[C@@H]1[C@H](C(CC(=O)N1Cc1cccnc1)c1ccccc1Br)[N+]([O-])=O

InChI Key InChIKey=WWFSTTKCQATYGJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128795   

LigandPNGBDBM50128795(4-(2-Bromo-phenyl)-6-(3,4-dihydroxy-phenyl)-5-nitr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain farnesyltransferase (FTase) farnesylation of viral K-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50128795(4-(2-Bromo-phenyl)-6-(3,4-dihydroxy-phenyl)-5-nitr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of bovine brain farnesyltransferase (FTase) farnesylation of viral K-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50128795(4-(2-Bromo-phenyl)-6-(3,4-dihydroxy-phenyl)-5-nitr...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine brain farnesyltransferase (FTase) farnesylation of viral K-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed