BDBM50128787 4-[4-(2-Bromo-phenyl)-3-nitro-1-pyridin-3-ylmethyl-piperidin-2-yl]-benzene-1,2-diol::CHEMBL81532

SMILES Oc1ccc(cc1O)[C@@H]1[C@H](C(CCN1Cc1cccnc1)c1ccccc1Br)[N+]([O-])=O

InChI Key InChIKey=NMYPTUIZBNECAG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128787   

LigandPNGBDBM50128787(4-[4-(2-Bromo-phenyl)-3-nitro-1-pyridin-3-ylmethyl...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of bovine brain farnesyltransferase (FTase) farnesylation of viral K-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50128787(4-[4-(2-Bromo-phenyl)-3-nitro-1-pyridin-3-ylmethyl...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of bovine brain farnesyltransferase (FTase) farnesylation of viral K-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50128787(4-[4-(2-Bromo-phenyl)-3-nitro-1-pyridin-3-ylmethyl...)
Affinity DataIC50: 310nMAssay Description:Inhibition of bovine brain farnesyltransferase (FTase) farnesylation of viral K-RasMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed