BDBM50128733 7-[2-(Biphenyl-4-sulfonylamino)-6,6-dimethyl-bicyclo[3.1.1]hept-3-yl]-hept-5-enoic acid::CHEMBL420588

SMILES CC1(C)[C@@H]2C[C@H]1[C@H](NS(=O)(=O)c1ccc(cc1)-c1ccccc1)[C@@H](C\C=C/CCCC(O)=O)C2

InChI Key InChIKey=VLZBULDOJODFQV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128733   

TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50128733(7-[2-(Biphenyl-4-sulfonylamino)-6,6-dimethyl-bicyc...)
Affinity DataIC50: 1.20E+3nMAssay Description:Prostaglandin D2 receptor antagonist activity, evaluated by inhibition of [3H]PGD-2 binding to human platelet membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Shionogi

Curated by ChEMBL
LigandPNGBDBM50128733(7-[2-(Biphenyl-4-sulfonylamino)-6,6-dimethyl-bicyc...)
Affinity DataIC50: 530nMAssay Description:Concentration required to inhibit the PGD-2 evoked cAMP formation in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed