BDBM50128681 CHEMBL80933::N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-dimethylaminomethyl-phenyl)-vinyl]-nicotinamide

SMILES CN(C)Cc1ccc(\C=C\c2ncccc2C(=O)NC(Cc2ccccc2)C(N)=O)cc1

InChI Key InChIKey=OXQKFIHVHFGYRB-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50128681   

TargetCalpain-1 catalytic subunit(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50128681(N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-dimethylami...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of degradation of tyrosine kinase pp60src by Calpain 1 in human plateletsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCalpain-1 catalytic subunit(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50128681(N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-dimethylami...)
Affinity DataKi:  18.3nMAssay Description:Inhibitory activity against human Calpain 1 isolated from erythrocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Abbott

Curated by ChEMBL
LigandPNGBDBM50128681(N-(1-Carbamoyl-2-phenyl-ethyl)-2-[2-(4-dimethylami...)
Affinity DataKi:  83nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed