BDBM50128663 4-(4-Methoxy-benzenesulfonyl)-1-naphthalen-2-ylmethyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL312429::N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(naphthalen-2-ylmethyl)piperidine-4-carboxamide

SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc3ccccc3c2)CC1)C(=O)NO

InChI Key InChIKey=GNNAXEPAOIUDTH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128663   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128663(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(naphthale...)
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128663(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(naphthale...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50128663(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(naphthale...)
Affinity DataIC50: 170nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128663(N-hydroxy-4-(4-methoxyphenylsulfonyl)-1-(naphthale...)
Affinity DataIC50: 368nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed