BDBM50128651 4-(4-(4-chlorophenoxy)phenylsulfonyl)-1-ethyl-N-hydroxypiperidine-4-carboxamide::4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-piperidine-4-carboxylic acid hydroxyamide::CHEMBL78549

SMILES CCN1CCC(CC1)(C(=O)NO)S(=O)(=O)c1ccc(Oc2ccc(Cl)cc2)cc1

InChI Key InChIKey=AUWOIDNULNLPBA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128651   

TargetMatrix metalloproteinase-9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128651(4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-p...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128651(4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-p...)
Affinity DataIC50: 1nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
LigandPNGBDBM50128651(4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-p...)
Affinity DataIC50: 413nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128651(4-[4-(4-Chloro-phenoxy)-benzenesulfonyl]-1-ethyl-p...)
Affinity DataIC50: 1.72E+3nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMed