BDBM50128383 (S)-1-[4-(5-Fluoro-benzo[b]thiophen-2-yl)-piperidin-1-yl]-3-(2-methyl-1H-indol-4-yloxy)-propan-2-ol::CHEMBL293065

SMILES Cc1cc2c(OC[C@@H](O)CN3CCC(CC3)c3cc4cc(F)ccc4s3)cccc2[nH]1

InChI Key InChIKey=WPCKJGIJFBQUPQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50128383   

TargetSodium-dependent serotonin transporter(Rat)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128383((S)-1-[4-(5-Fluoro-benzo[b]thiophen-2-yl)-piperidi...)
Affinity DataKi:  5.30nMAssay Description:Binding affinity towards serotonin [5-HT] reuptake site labeled with [3H]paroxetine as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128383((S)-1-[4-(5-Fluoro-benzo[b]thiophen-2-yl)-piperidi...)
Affinity DataKi:  7.5nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor using [3H]8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed