BDBM50128289 4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dihydro-1H-pyrrol-3-yl]-indol-1-yl}-piperidine-1-carboxylic acid tert-butyl ester::CHEMBL293805

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2cn(C3CCN(CC3)C(=O)OC(C)(C)C)c3ccccc23)c2ccccc12

InChI Key InChIKey=FZXZDHDSQPECTD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50128289   

TargetProtein kinase C alpha type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Protein kinase C alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 200nMAssay Description:Inhibition of Protein kinase C beta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C eta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Protein kinase C etaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C delta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Protein kinase C deltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C zeta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Protein kinase C zetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C epsilon type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Protein kinase C epsilonMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C gamma type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Protein kinase C gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProtein kinase C beta type(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128289(4-{3-[4-(1-Methyl-1H-indol-3-yl)-2,5-dioxo-2,5-dih...)
Affinity DataIC50: 80nMAssay Description:Inhibition of Protein kinase C beta 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed