BDBM50128184 3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-(dimethylamino)phenoxy)phenyl)amino)-1,1,1-trifluoropropan-2-ol::3-((3-(3-(dimethylamino)phenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)-1,1,1-trifluoropropan-2-ol::3-{[3-(3-Dimethylamino-phenoxy)-phenyl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-1,1,1-trifluoro-propan-2-ol::CHEMBL305003

SMILES CN(C)c1cccc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)c1

InChI Key InChIKey=NOVSYOAFPGEWMY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128184   

TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128184(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-(dim...)
Affinity DataIC50: 200nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128184(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-(dim...)
Affinity DataIC50: 200nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50128184(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-(dim...)
Affinity DataIC50: 200nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128184(3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(3-(dim...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of CETP (unknown origin)-mediated [3H]cholesteryl ester transfer from HDL donor particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article