BDBM50128181 1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-[3-(1,1,2,2-tetrafluoro-ethoxy)-benzyl]-amino}-propan-2-ol::1,1,1-trifluoro-3-((3-(4-propoxyphenoxy)phenyl)(3-(1,1,2,2-tetrafluoroethoxy)benzyl)amino)propan-2-ol::3-((3-(1,1,2,2-tetrafluoroethoxy)benzyl)(3-(4-propoxyphenoxy)phenyl)amino)-1,1,1-trifluoropropan-2-ol::CHEMBL71379

SMILES CCCOc1ccc(Oc2cccc(c2)N(CC(O)C(F)(F)F)Cc2cccc(OC(F)(F)C(F)F)c2)cc1

InChI Key InChIKey=JGULPENQLDMDPJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50128181   

TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128181(1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-...)
Affinity DataIC50: 3.42E+4nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128181(1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-...)
Affinity DataIC50: 400nMAssay Description:Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in bufferMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128181(1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of CETPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Rabbit)
Al-Zaytoonah Private University of Jordan

Curated by ChEMBL
LigandPNGBDBM50128181(1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-...)
Affinity DataIC50: 400nMAssay Description:Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50128181(1,1,1-Trifluoro-3-{[3-(4-propoxy-phenoxy)-phenyl]-...)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of CETP (unknown origin)-mediated [3H]cholesteryl ester transfer from HDL donor particles to LDL acceptor particlesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article