BDBM50127708 (1H)-indole-3-carbonitrile::1H-Indole-3-carbonitrile::CHEMBL46724

SMILES c1ccc2c(c1)c(c[nH]2)C#N

InChI Key InChIKey=CHIFTAQVXHNVRW-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50127708   

TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50127708(1H-Indole-3-carbonitrile | (1H)-indole-3-carbonitr...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50127708(1H-Indole-3-carbonitrile | (1H)-indole-3-carbonitr...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of IMPDH2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1/2(Human)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50127708(1H-Indole-3-carbonitrile | (1H)-indole-3-carbonitr...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2018
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Mouse)
University of Namur

Curated by ChEMBL
LigandPNGBDBM50127708(1H-Indole-3-carbonitrile | (1H)-indole-3-carbonitr...)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2013
Entry Details Article
PubMed