BDBM50127581 2-(4,5-Dihydro-1H-imidazol-2-yl)-1,2,7,8,9,10-hexahydro-3-oxa-10a-aza-cyclohepta[de]naphthalene::CHEMBL418716

SMILES C1CN=C(N1)C1CN2CCCCc3cccc(O1)c23

InChI Key InChIKey=CEAKDQVDDQMVIY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127581   

TargetNischarin(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50127581(2-(4,5-Dihydro-1H-imidazol-2-yl)-1,2,7,8,9,10-hexa...)
Affinity DataKi:  631nMAssay Description:Binding affinity for imidazoline receptor I-2 in rabbit kidney homogenate (relative to [3H]-Idazoxan radioligand)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNischarin(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50127581(2-(4,5-Dihydro-1H-imidazol-2-yl)-1,2,7,8,9,10-hexa...)
Affinity DataKi:  643nMAssay Description:In vitro binding affinity determined against imidazoline receptor I-2 using rabbit kidney preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNischarin(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50127581(2-(4,5-Dihydro-1H-imidazol-2-yl)-1,2,7,8,9,10-hexa...)
Affinity DataKi:  2.44E+3nMAssay Description:In vitro binding affinity determined against imidazoline receptor I-1 from rabbit kidney preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed