BDBM50127574 2-(4,5-Dihydro-1H-imidazol-2-yl)-6-methoxy-4-methyl-3,4-dihydro-2H-benzo[1,4]oxazine::CHEMBL274315

SMILES COc1ccc2OC(CN(C)c2c1)C1=NCCN1

InChI Key InChIKey=TZTTVGMGHGDZRY-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127574   

TargetNischarin(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50127574(2-(4,5-Dihydro-1H-imidazol-2-yl)-6-methoxy-4-methy...)
Affinity DataKi:  63nMAssay Description:Binding affinity for imidazoline receptor I-2 in rabbit kidney homogenate (relative to [3H]-Idazoxan radioligand)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetNischarin(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50127574(2-(4,5-Dihydro-1H-imidazol-2-yl)-6-methoxy-4-methy...)
Affinity DataKi:  78.6nMAssay Description:In vitro binding affinity determined against imidazoline receptor I-1 from rabbit kidney preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNischarin(Human)
Orleans University

Curated by ChEMBL
LigandPNGBDBM50127574(2-(4,5-Dihydro-1H-imidazol-2-yl)-6-methoxy-4-methy...)
Affinity DataKi:  79nMAssay Description:In vitro binding affinity determined against imidazoline receptor I-1 from rabbit kidney preparationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed