BDBM50127439 CHEMBL3628187

SMILES COc1ccc(cc1C#N)-c1nc(C)c(C(O)=O)n1O

InChI Key InChIKey=WJTCAHCTRXGVOG-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127439   

TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127439(CHEMBL3628187)
Affinity DataIC50: 550nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127439(CHEMBL3628187)
Affinity DataIC50: 501nMAssay Description:Inhibition of bovine XO using xanthine as substrate after 120 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2016
Entry Details Article
PubMed
TargetCoagulation factor XI(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127439(CHEMBL3628187)
Affinity DataKi:  2.43E+5nMAssay Description:Binding affinity to coagulation factor 11a (unknown origin) assessed as inhibition constant using (p-Glu-Pro-Arg-pNa,HCl) as substrate preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2022
Entry Details Article
PubMed