BDBM50127326 6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-2-(3,4-dichloro-phenyl)-nicotinonitrile::CHEMBL38567

SMILES Cn1cncc1C(OCc1ccc(C#N)c(n1)-c1ccc(Cl)c(Cl)c1)c1ccc(cc1)C#N

InChI Key InChIKey=OFHZJNIDVREURX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127326   

TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127326(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127326(6-[(4-Cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-me...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed