BDBM50127316 5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-nicotinonitrile::CHEMBL39117

SMILES Cn1cncc1C(OCc1ncc(cc1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=QMHTYBBGJXNNQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127316   

TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127316(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127316(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed