BDBM50127309 4-{6-Cyano-3-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-pyridin-2-yl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL41518

SMILES Cn1cncc1C(OCc1ccc(nc1N1CCN(CC1)C(=O)OC(C)(C)C)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=BLLWRZKPPHTMHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127309   

TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127309(4-{6-Cyano-3-[(4-cyano-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 42nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127309(4-{6-Cyano-3-[(4-cyano-phenyl)-(3-methyl-3H-imidaz...)
Affinity DataIC50: 44nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed