BDBM50127303 5-[(3'-Chloro-5-cyano-4'-fluoro-biphenyl-2-ylmethoxy)-(3-methyl-3H-imidazol-4-yl)-methyl]-pyridine-2-carbonitrile::CHEMBL41682

SMILES Cn1cncc1C(OCc1ccc(cc1-c1ccc(F)c(Cl)c1)C#N)c1ccc(nc1)C#N

InChI Key InChIKey=XBLAJQIOYXLORX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127303   

TargetGeranylgeranyl transferase type-1 subunit beta(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127303(5-[(3'-Chloro-5-cyano-4'-fluoro-biphenyl-2-ylmetho...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50127303(5-[(3'-Chloro-5-cyano-4'-fluoro-biphenyl-2-ylmetho...)
Affinity DataIC50: 1nMAssay Description:Inhibition of transfer of [3H]FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed