BDBM50127257 6-(3-Chloro-phenyl)-8-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-oxazolo[5,4,3-ij]quinolin-4-one::CHEMBL39274

SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1cc2OCn3c2c(c1)c(cc3=O)-c1cccc(Cl)c1

InChI Key InChIKey=UKMSOESJBYSCKH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127257   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50127257(6-(3-Chloro-phenyl)-8-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50: 6nMAssay Description:Inhibition of [3H]FPP incorporation into biotinylated laminB peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed