BDBM50127251 7-[Amino-(4-chloro-phenyl)-(3-methyl-3H-imidazol-4-yl)-methyl]-5-(3-chloro-phenyl)-1-methyl-1,5-dihydro-benzo[e][1,4]oxazepin-2-one::CHEMBL290456

SMILES CN1c2ccc(cc2C(OCC1=O)c1cccc(Cl)c1)C(N)(c1cncn1C)c1ccc(Cl)cc1

InChI Key InChIKey=WAHSFNMXOHAFIQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127251   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50127251(7-[Amino-(4-chloro-phenyl)-(3-methyl-3H-imidazol-4...)
Affinity DataIC50: 48nMAssay Description:Inhibition of farnesyl transferase at 0.1 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed