BDBM50127215 3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-ylmethoxy]-phenyl}-propionic acid::CHEMBL288341

SMILES Cc1nc(sc1COc1ccc(CCC(O)=O)cc1)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=MAJOKGVPWQXGOQ-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50127215   

TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127215(3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazo...)
Affinity DataEC50:  90nMAssay Description:Maximum transcriptional activation of human PPAR delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127215(3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazo...)
Affinity DataIC50: 30nMAssay Description:Binding affinity for human PPAR delta receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127215(3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazo...)
Affinity DataEC50:  7.04E+3nMAssay Description:Maximum transcriptional activation of human PPAR gamma receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127215(3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazo...)
Affinity DataEC50:  3.00E+3nMAssay Description:Maximum transcriptional activation of human PPAR alpha receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50127215(3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazo...)
Affinity DataEC50:  376nMAssay Description:Transactivation of GAL4-fused human PPARdelta LBD expressed in HEK293 cells after 18 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Guangdong Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50127215(3-{4-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazo...)
Affinity DataEC50:  325nMAssay Description:Agonist activity at human FFA1 receptor expressed in CHO cells by Fluo 4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed