BDBM50127145 6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenyl]-hex-5-ynoic acid::CHEMBL37334
SMILES COc1ccc(cc1Cc1cnc(N)nc1N)C#CCCCC(O)=O
InChI Key InChIKey=ZXBPOEANGCIFEL-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50127145
Affinity DataIC50: 7.80nMAssay Description:Inhibitory concentration against Mycobacterium avium dihydrofolate reductaseMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory concentration against Toxoplasma gondii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against Pneumocystis carinii dihydrofolate reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 7.80nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Mycobacterium aviumMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibitory activity against Dihydrohydrofolate reductase(DHFR) of Toxoplasma gondiiMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of Dihydrohydrofolate reductase(DHFR) of Pneumocystis cariniiMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition Dihydrohydrofolate reductase(DHFR) of rat liverMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibitory activity against rat dihydrofolate reductaseMore data for this Ligand-Target Pair