BDBM50127040 CHEMBL45113::N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}pentyl)-N'-nitroguanidine

SMILES NCCc1ccc(NC[C@@H](N)CCCNC(=N)N[N+]([O-])=O)cc1

InChI Key InChIKey=JJADHNQTHMUGOW-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50127040   

TargetNitric oxide synthase, brain(Rat)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127040(N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}p...)
Affinity DataKi:  1.66E+3nMAssay Description:Inhibitory activity against Neuronal Nitric Oxide Synthase (nNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127040(N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}p...)
Affinity DataKi:  1.66E+3nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127040(N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}p...)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127040(N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}p...)
Affinity DataKi:  4.14E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127040(N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}p...)
Affinity DataKi:  3.60E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127040(N-((4S)-4-amino-5-{[4-(2-aminoethyl)phenyl]amino}p...)
Affinity DataKi:  4.14E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed