BDBM50126620 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-7-trifluoromethyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL287820::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-7-(trifluoromethyl)quinoline-3-carboxamide

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2cc(ccc12)C(F)(F)F)C(=O)NO

InChI Key InChIKey=NVQUYHFBHXGQLL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50126620   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126620(N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126620(N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 77nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126620(N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126620(N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126620(N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)pheny...)
Affinity DataIC50: 78nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed