BDBM50126615 4-(4-(but-2-ynyloxy)-N-methylphenylsulfonamido)-N-hydroxy-8-methoxyquinoline-3-carboxamide::4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]-8-methoxy-quinoline-3-carboxylic acid hydroxyamide::CHEMBL288671

SMILES COc1cccc2c(N(C)S(=O)(=O)c3ccc(OCC#CC)cc3)c(cnc12)C(=O)NO

InChI Key InChIKey=DWBZTKJXPJGGSU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50126615   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 33nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 857nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 9nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 871nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50126615(4-[(4-But-2-ynyloxy-benzenesulfonyl)-methyl-amino]...)
Affinity DataIC50: 17nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed