BDBM50126605 4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-8-phenyl-quinoline-3-carboxylic acid hydroxyamide::CHEMBL290952::N-hydroxy-4-(4-methoxy-N-(pyridin-3-ylmethyl)phenylsulfonamido)-8-phenylquinoline-3-carboxamide

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1cccnc1)c1c(cnc2c(cccc12)-c1ccccc1)C(=O)NO

InChI Key InChIKey=JRKVJTDYMGJJAK-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50126605   

TargetMatrix metalloproteinase-9(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against matrix metalloprotease 9 (MMP-9).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 151nMAssay Description:Inhibitory activity against matrix metalloprotease 1 (MMP-1).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against matrix metalloprotease 13 (MMP-13).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 120nMAssay Description:Inhibitory activity against TACE.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 151nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMed
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of TACEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth-Ayerst Research

Curated by ChEMBL
LigandPNGBDBM50126605(4-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed