BDBM50126426 CHEMBL440797::N*1*-[7-(4-Thiophen-3-yl-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine::N1-(7-(4-(thiophen-3-yl)phenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine

SMILES NCCCNc1nc(cc2ncccc12)-c1ccc(cc1)-c1ccsc1

InChI Key InChIKey=MVCGOFVBSSIGJA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50126426   

TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126426(N1-(7-(4-(thiophen-3-yl)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against spleen tyrosine kinase (SYK)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50126426(N1-(7-(4-(thiophen-3-yl)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant SykMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed